Long name
Recombinant Human GDNF family receptor alpha-3 (GFRA3)
Alternative names
GDNF family receptor alpha-3 preproprotein; GDNF family receptor alpha-3; GDNF family receptor alpha-3; GFR-alpha-3; GDNFR-alpha-3; GPI-linked receptor; GDNF receptor alpha-3; glial cell line-derived neurotrophic factor receptor alpha-3; GDNF family receptor alpha 3;
Gene name
GFRA3
Other gene names
GFRA3; GFRA3; GDNFR3; GDNF receptor alpha-3; GDNFR-alpha-3; GFR-alpha-3
General description
GDNF family receptor alpha-3 (GFRA3) is a recombinant protein expressed in E. coli. The protein can be with or without a His-Tag or other tag in accordance to customer's request. All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility.
Product category
Recombinant Proteins
Expression system
E. coli
Available also expressed in:
E Coli ; Yeast ; Baculovirus ; Mammalian Cell
Purity
Greater than 90% (determined by SDS-PAGE)
Form
Lyophilized protein
Storage
This protein can be stored at -20 degrees Celsius. For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius. Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains.
Applications
This protein can be used as a positive control for applications such as ELISA, IFA, RIA, Western Blot, etc.
Description
The GDNF family receptor alpha-3 (GFRA3) is a α- or alpha protein sometimes glycoprotein present in blood.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.