c-erbB2 (Herstatin, V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) CD340, C-erbB-2, HER2, HER-2, HER-2/neu, MLN 19, NEU proto-oncogene, NGL, p185erbB2, Receptor tyrosine-protein kinase erbB-2

Basic informations

  • Size: 100ug
  • Catalog number: GEN607091
  • Price: 614.00EUR
c-erbB2 (Herstatin, V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) CD340, C-erbB-2, HER2, HER-2, HER-2/neu, MLN 19, NEU proto-oncogene, NGL, p185erbB2, Receptor tyrosine-protein kinase erbB-2

Also known as

c-erbB2

Other names

Chain P, Single Chain Fv Of C219 Heavy Chain V101l Mutant In Complex With Synthetic Epitope Peptide; N/A

Category

Antibodies

Subcategory

Mnoclonal antibodies

Gene name

N/A

Gene name synonims

N/A

Other gene names

N/A

Clonality

Monoclonal

Immunoglobulin isotype

IgG2b

Clone

9H75

Host organism

Mouse (Mus musculus)

Source organism

Human (Homo sapiens)

Species reactivity

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Specificity and cross-reactivity

Recognizes recombinant human Herstatin and recombinant human ErbB2. Does not crossreact with recombinant human EGFR or recombinant human ERbB3.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Purification method

Affinity Purified by Protein G affinity chromatography.

Form/Appearance

Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.

Concentration

N/A

Storage and shipping

Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.

Tested applications:

Immunohistochemistry (IHC)

Virus

leukemia

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.