TrkC (Tyrosine Kinase Receptor C, Trk C, Trk-C Tyrosine Kinase, EC 2.7.10.1, ETS-related Protein Neurotrophic Receptor Tyrosine Kinase Fusion, ETV6 NTRK3 Fusion, GP145 TrkC, gp145(TrkC), GP145-TrkC, Neurotrophic Tyrosine Kinase Receptor Type 3, NTRK 3, NT

Basic informations

  • Size: 100ug
  • Catalog number: GEN605705
  • Price: 801.00EUR
TrkC (Tyrosine Kinase Receptor C, Trk C, Trk-C Tyrosine Kinase, EC 2.7.10.1, ETS-related Protein Neurotrophic Receptor Tyrosine Kinase Fusion, ETV6 NTRK3 Fusion, GP145 TrkC, gp145(TrkC), GP145-TrkC, Neurotrophic Tyrosine Kinase Receptor Type 3, NTRK 3, NT

Also known as

TrkC

Other names

trkC; NT-3 growth factor receptor; NT-3 growth factor receptor; trk-C; GP145-TrkC; ETV6-NTRK3 fusion; OTTHUMP00000192915; OTTHUMP00000240515; trkC tyrosine kinase; neurotrophin 3 receptor; tyrosine kinase receptor C; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; neurotrophic tyrosine kinase, receptor, type 3; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase

Category

Antibodies

Subcategory

Mnoclonal antibodies

Gene name

NTRK3; NTRK3; TRKC; gp145(trkC); TRKC

Gene name synonims

NTRK3; NTRK3; TRKC; gp145(trkC); TRKC

Other gene names

NTRK3; NTRK3; TRKC; gp145(trkC); TRKC

Clonality

Monoclonal

Immunoglobulin isotype

IgG1

Clone

9F395

Host organism

Rat (Rattus norvegicus)

Source organism

Mouse (Mus musculus)

Species reactivity

Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Specificity and cross-reactivity

Recognizes mouse TrkC. Does not react with mouse TrkB.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Purification method

Purified

Form/Appearance

Supplied as a lyophilized powder in PBS. Reconstitute in 500ul 40-50% glycerol, PBS.

Concentration

N/A

Storage and shipping

Lyophilized powder Store the antibody at +4 degrees Celsius for short term storage.. Reconstitute to nominal volume by adding sterile 40-50% glycerol and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 3 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Tested applications:

Western Blot (WB)

Description

Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.