Nerve Growth Factor Receptor, p75 (NGFR, NGF Receptor, CD271, Gp80 LNGFR, Low Affinity Nerve Growth Factor Receptor, Low Affinity Neurotrophin Receptor p75 NTR, p75 ICD, p75 Neurotrophin, p75 NTR, Tumor Necrosis Factor Receptor Superfamily Member 16, TNFR

Basic informations

  • Size: 100ug
  • Catalog number: GEN604353
  • Price: 652.00EUR
Nerve Growth Factor Receptor, p75 (NGFR, NGF Receptor, CD271, Gp80 LNGFR, Low Affinity Nerve Growth Factor Receptor, Low Affinity Neurotrophin Receptor p75 NTR, p75 ICD, p75 Neurotrophin, p75 NTR, Tumor Necrosis Factor Receptor Superfamily Member 16, TNFR

Also known as

Nerve Growth Factor Receptor, p75

Other names

nerve growth factor receptor; N/A; nerve growth factor receptor; N/A; N/A

Category

Antibodies

Subcategory

Mnoclonal antibodies

Gene name

NGFR; N/A; N/A; N/A

Gene name synonims

NGFR; N/A; N/A; N/A

Other gene names

NGFR; N/A; N/A; N/A

Clonality

Monoclonal

Immunoglobulin isotype

IgG

Clone

9G392

Host organism

Mouse (Mus musculus)

Source organism

Human (Homo sapiens)

Species reactivity

Canine, Feline, Human (Homo sapiens), Porcine, Rabbit (Oryctolagus cuniculus), Sheep; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Specificity and cross-reactivity

Recognizes human p75NTR (low affinity neurotrophin receptor). Species Crossreactivity: feline, canine, porcine, rabbit and sheep. Does not react with rat or mouse.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Purification method

Affinity Purified by affinity chromatography.

Form/Appearance

Supplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O.

Concentration

N/A

Storage and shipping

Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. Aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Tested applications:

ELISA (EL/EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)

Tissue

nerve, tumor

Test

A high affinity purification column was use to purify Nerve Growth Factor Receptor, p75 (NGFR, NGF Receptor, CD271, Gp80 LNGFR, Nerve Growth Factor Receptor, Neurotrophin Receptor p75 NTR, p75 ICD, p75 Neurotrophin, p75 NTR, Tumor Necrosis Factor Receptor Superfamily Member 16, TNFR by MBS Monoclonals by chromatographic size exclusion.

Description

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.