Also known as
Nerve Growth Factor Receptor, p75
Other names
nerve growth factor receptor; N/A; nerve growth factor receptor; N/A; N/A
Category
Antibodies
Subcategory
Mnoclonal antibodies
Gene name
NGFR; N/A; N/A; N/A
Gene name synonims
NGFR; N/A; N/A; N/A
Other gene names
NGFR; N/A; N/A; N/A
Clonality
Monoclonal
Immunoglobulin isotype
IgG1,k
Clone
0.N.469
Host organism
Mouse (Mus musculus)
Source organism
Human (Homo sapiens)
Species reactivity
Feline, Human (Homo sapiens), Monkey, Rabbit (Oryctolagus cuniculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes human Nerve Growth Factor Receptor (p75NGFR). Species Crossreactivity: Monkey (Cebus apella, Macaca fascicularis, Mulatta and Nemestrina), baboon (Papio anubis and Cynocephalus), feline, rabbit and ferret. Does not crossreact with mouse or rat.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Purification method
Affinity Purified by Protein G affinity chromatography.
Form/Appearance
Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.1% sodium azide. Also available without BSA and azide.
Concentration
N/A
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested applications:
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
Tissue
nerve
Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.