NPS/Neuropeptide S Antibody, ALEXA FLUOR 488

Basic informations

  • Size: 100ul
  • Catalog number: bs-11429R-A488
  • Price: 380.00EUR
NPS/Neuropeptide S Antibody, ALEXA FLUOR 488

Long name

NPS/Neuropeptide S Polyclonal Antibody, ALEXA FLUOR 488 Conjugated

Also known as

Anti-NPS/Neuropeptide S PAb ALEXA FLUOR 488

Category

Conjugated Primary Antibodies

Conjugated with

ALEXA FLUOR® 488

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

NPS/Neuropeptide S

Specificity

This is a highly specific antibody against NPS/Neuropeptide S.

Modification

Unmodified

Modification Site

None

Clonality

Polyclonal

Clone

Polyclonal antibody

Concentration

1ug per 1ul

Source

KLH conjugated synthetic peptide derived from rat Neuropeptide S

Gene ID Number

100360071

Tested applications

IF(IHC-P)

Recommended dilutions

IF(IHC-P)(1:50-200)

Crossreactivity

Rat

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Background of the antigen

Neuropeptides are regulators of synaptic transmission and their effects are mediated by G-protein coupled receptors. NPS (Neuropeptide S) is a 20 amino acid peptide cleaved from a larger precursor that contains a hydrophobic signal peptide and proteolytic cleavage processing sites. The N-terminal residue of NPS is always a serine regardless of the species. NPS is predominantly found in the central nervous system and plays an important role regulating sleep/wake functions, locomotion, arousal/anxiety responses and food intake. NPS functions by binding and activating its receptor, NPSR, and increasing intracellular calcium levels thereby acting as an excitatory transmitter. In addition, NPS stimulates the hypothalamo-pituitary adrenal (HPA) axis via the release of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP). NPS and its receptor NPSR may also play a role in asthma pathogenesis.

Purification

Purified by Protein A.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Excitation emission

499nm/519nm

Synonyms

NeuropeptideS; Neuropeptide-S; NPS; NPS_RAT.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-NPS/Neuropeptide S has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Conjugation

Alexa Fluor

French translation

anticorps