NeuroD1 Antibody, ALEXA FLUOR 350

Basic informations

  • Size: 100ul
  • Catalog number: bs-1517R-A350
  • Price: 380.00EUR
NeuroD1 Antibody, ALEXA FLUOR 350

Long name

NeuroD1 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated

Also known as

Anti-NeuroD1 PAb ALEXA FLUOR 350

Category

Conjugated Primary Antibodies

Conjugated with

ALEXA FLUOR® 350

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

NeuroD1

Specificity

This is a highly specific antibody against NeuroD1.

Modification

Unmodified

Modification Site

None

Clonality

Polyclonal

Clone

Polyclonal antibody

Concentration

1ug per 1ul

Immunogen range

1-50/356

Subcellular location

Cytoplasm, Nucleus

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NeuroD1

Gene ID Number

4760

Swiss Prot

Q13562

Tested applications

IF(IHC-P)

Recommended dilutions

IF(IHC-P)(1:50-200)

Crossreactivity

Human, Mouse, Rat

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Background of the antigen

Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).

Purification

Purified by Protein A.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Excitation emission

343nm/442nm

Synonyms

BETA2; BHF-1; MODY6; NEUROD; bHLHa3; Neurogenic differentiation factor 1; NeuroD1; Class A basic helix-loop-helix protein 3

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Conjugation

Alexa Fluor,ALEXA FLUOR 350

French translation

anticorps