Rabbit Anti Human,Mouse NEUROD1 Antibody-Non-conjugated

Basic informations

  • Size: 100ug
  • Catalog number: CSB-PA615700LA01HU_100ug
  • Price: 302.00EUR
Rabbit Anti Human,Mouse NEUROD1 Antibody-Non-conjugated

Long name

Rabbit Antibody against Human, Mouse NEUROD1, Non-conjugated

Synonym name

NEUROD1 Human, Mouse Antibody

Species reactivity

Human,Mouse

Tested applications & recommended dilutions

ELISA,WB,IF;Recommended dilution:WB:1:200-1:2000,IF:1:50-1:200

Conjugation

Non-conjugated

Antibody isotype

IgG

UniProt ID

Q13562

Format

Liquid, diluted in buffer

Buffer composition

Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Purity

>95%

Purification method

Protein G purified

Antibody category

Polyclonal Antibodies

Immunogen type

Recombinant Human Neurogenic differentiation factor 1 protein (154-356AA)

Immunogen species

Human

Alias

Neurogenic differentiation factor 1,NeuroD,NeuroD1,Class A basic helix-loop-helix protein 3,bHLHa3,NEUROD1,BHLHA3,NEUROD

Background

Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).

Clonality

Polyclonal antibody

Shipping and storage

NEUROD1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.

Short name of the antigen

Neurogenic differentiation factor 1

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.

Properties

If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Latin name

Mus musculus,Oryctolagus cuniculus

About

Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.

French translation

anticorps