Category
Antibody
Concentration
0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Form
Purified
Conjugation
Unconjugated
Clone
Polyclonal antibody
Recognised antigen
Neurotensin Receptor 2
Host animal
Rabbit (Oryctolagus cuniculus)
Clonality
Polyclonal (rabbit origin)
Species reactivity
Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
Tested applications
WB
Recommended dilutions
Western blot: 1-3ug/ml
Notes
Provided assay concentrations are suggestions only, Neurotensin Receptor 2 antibody titration may be required for optimal results.
Added buffer
1X Phosphate Buffered Saline (PBS), pH 7.4
Intented use
This Neurotensin Receptor 2 antibodyis to be used only for research purposes and not for diagnostics..
Gene ID #
23620
Purity
This antibody was purified by Protein A method
Description
Neurotensin is a central nervous system protein involved with the regulation and release of Luteinizing hormone (Lutropin), which regulates ovulation in females and testosterone production in males, and Prolactin (Luteotropin), which enables milk production in female mammals. The GPCR Neurotensin receptor 2 (NTSR2) is one of three receptors for Neurotensin (NTSR1-3). Unlike NTSR1, NTSR2 has only a low affinity for Neurotensin, but high affinity for levocabastine, a histamine H1 receptor antagonist that can block Neurotensin binding to NTSR2 but not affect its binding to NTSR1.
Immunogen
A recombinant protein fragment from the N-terminal half of human Neurotensin Receptor 2 was used as the immunogen for this antibody.
Storage
Aliquot the Neurotensin Receptor 2 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
Properties
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Additional description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
French translation
anticorps