Type
Conjugated Primary Antibody
Conjugated with
ALEXA FLUOR® 594
Host organism
Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide
Neurokinin A Receptor
Specificity
This antibody reacts specifically with Neurokinin A Receptor
Modification
No modification has been applied to this antibody
Modification site
None
Clonality
Polyclonal Antibody
Clone
Polyclonal Antibodies
Concentration
1ug per 1ul
Subcellular locations
Extracellular
Antigen Source
KLH conjugated synthetic peptide derived from human NK2R
Gene ID
6865
Swiss Prot
P21452
Applications
IF(IHC-P)
Applications with corresponding dilutions
IF(IHC-P)(1:50-200)
Cross reactive species
Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Cross Reactive Species details
No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Background information
This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.
Purification method
Purified by Protein A.
Storage
Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission
590nm/617nm
Synonyms
SKR; NK2R; NKNAR; TAC2R; Substance-K receptor; NK-2 receptor; NK-2R; Neurokinin A receptor; Tachykinin receptor 2; TACR2
Also known as
Neurokinin A Receptor Antibody
Other name
Anti-Neurokinin A Receptor
Advisory
Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Properties
For facs or microscopy Alexa 1 conjugate.
Conjugation
Alexa Fluor,ALEXA FLUOR® 594
Conjugated
Alexa conjugate 1
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.