BDNF Antibody

Basic informations

  • Size: 0,1 mg
  • Catalog number: PA1014
  • Price: 320.00EUR
BDNF Antibody

Target antigen

BDNF

Clonality

Polyclonal antibody

Clone

Polyclonal antibody

Raised in

rabbit

Type of the antibody

IgG polyclonal antibody

Product form

freeze-dried

Reacts with species:

human, rat Predicted to work with: mouse

Analyses

WB

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminal of human BDNF(129-148aa HSDPARRGELSVCDSISEWV), identical to the related rat and mouse sequences.

Product configuration

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Purification

Immunogen affinity purified.

Solubilization

The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml

Storage condtions

Keep the BDNF Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.

Tips

The BDNF Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.

Background

Brain derived neurotrophic factor(BDNF) is a member of the neurotrophin family of growth factors that includes NGF, NT3, and NT4. BDNF is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. BDNF is expressed within peripheral ganglia and is not restricted to neuronal target fields. BDNF has been purified and shown to reduce the amount of naturally occurring neuronal cell death in portions of the peripheral nervous system.

Related articles

1. Jones, K. R.; Reichardt, L. F. : Molecular cloning of a human gene that is a member of the nerve growth factor family. Proc. Nat. Acad. Sci. 87: 8060-8064, 1990. 2. Lee, R.; Kermani, P.; Teng, K. K.; Hempstead, B. L. : Regulation of cell survival by secreted proneurotrophins. Science 294: 1945-1948, 2001 . 3. Pruunsild, P.; Kazantseva, A.; Aid, T.; Palm, K.; Timmusk, T. : Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters. Genomics 90: 397-406, 2007.

Gene Name

BDNF

Protein Name

Brain-derived neurotrophic factor(BDNF)

Gene Full Name

brain-derived neurotrophic factor

Synonyms

Abrineurin antibody|BDNF antibody|BDNF_HUMAN antibody|Brain Derived Neurotrophic Factor antibody|Brain-derived neurotrophic factor antibody|MGC34632 antibody|Neurotrophin antibody

Uniprot ID

P23560

Properties

If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

French translation

anticorps