Description
Cell-permeable. A promoter of neurogenesis. Neurodazine induces neuronal differentiation in skeletal muscle cells. In mouse C2C12 myoblasts, neurodazine (2 μM for seven days) upregulated the expression of neuron-specific enolase (NSE), neurofilament 200 (NF200), synapsin, and other neuronal markers. Neurodazine similarly upregulated NSE and NF200 in human skeletal muscle fibers, indicating efficacy in mature muscle as well as in myoblasts.
Peptide sequence
N/A
CAS number
937807-66-4
Molecular weight
456.92
Category
Biochemicals
Other name
4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, methyl, 1-methylester diester
Molecular formula
C₂₇H₂₁ClN₂O₃
Physical appearance
Off-white solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
Yes
Purification
≥98% by HPLC
Reconstitute instructions
DMSO (~25 mg/ml) or EtOH (~ 25 mg/ml
Storage condition
-20°C
Shipping condition
Gel pack
Maximum time for storage
24 months
Storage instructions
Protect from air and light
Tissue
cell
Additional description
For cells, cell lines and tissues in culture till half confluency.