Synonyms
erbB-2, MNL 19, CD340, Neu, c-ErbB-2, NEU, NGL, TKR1
Alternates names
erbB-2, MNL 19, CD340, Neu, c-ErbB-2, NEU, NGL, TKR1
Taglines
Involved in the signal transduction pathways leading to cell growth and differentiation.
Biomolecule/Target
ERBB2
NCBI Gene ID #.
2064
NCBI Gene Symbol
ERBB2
Gene Source
Human
Accession #
P04626
Recombinant
Yes
Source
HEK 293 cells
Purity
N/A
Endotoxin Level
N/A
Activity (Specifications/test method)
Measured by its binding ability in a functional ELISA.
Biological activity
Immobilized Human Her2 (ED) at 0.05 μg/ml (100 μl/well) can bind trastuzumab (Herceptin) with a linear range of 0.05-3 ng/ml.
Results
N/A
Molecular Weight
70.6 kDa
Storage Temp.
-20°C
Shipping
Gel Pack
Shelf Life
1 year
Concentration
N/A
Appearance
Lyophilized
Physical form description
Lyophilized from 0.22 μm filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.
Reconstitution Instructions
Reconstitute in sterile deionized water to a concentration up to 0.2 mg/ml.
Handling
Centrifuge the vial prior to opening.
Usage
For Research Use Only! Not to be used in humans
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source
Recombinants or rec. proteins
Group
recombinants