anti-Neurofilament NF-M Antibody [3H11]

Gene info

Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.

Gene names

Nfm, Nef3, Nfm, 160 kDa neurofilament protein, NF-M

Antibodie's label

unlabelled serum

Purity

Total IgG fraction

Ab raised in

Mouse

Type

Monoclonal

Monoclonal

3H11

Immunoglobulin

IgG1

Spicific to

Specific for the ~145k Neurofilament M protein.

Antigen

Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E. coli.

Immuno application

Western Blot, immuno-histo-chemistry

Keep at

Neurofilament NF-M antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.

Works with

Human, Mouse, Rat, Chicken

Omim nr

128150

Ncbi nr

P12839

KDa

145

Vial with antibody

in solution

NCBI GENE nr

24588

GENE symbol

Nefm

Antigene name

neurofilament, medium polypeptide

Source

Rattus norvegicus

Protein nr

P12839

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

French translation

anticorps