Gene info
Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68 kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease.
Gene names
NFL, NF-L, NF68, CMT1F, CMT2E, NFL, 68 kDa neurofilament protein
Antibodie's label
unlabelled serum
Purity
Total IgY fraction
Ab raised in
Chicken
Type
Polyclonal
Spicific to
Specific for the ~68k Neurofilament L protein in Western blots and works well on frozen sections, cells in tissue culture and on mildly formalin fixed histological sections.
Antigen
Preparation of bovine spinal cord intermediate filaments
Immuno application
Western Blot, immuno-histo-chemistry
Keep at
Neurofilament NF-L antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
Works with
Human, Mouse, Rat, Bovine, Chicken
Omim nr
62511894
Ncbi nr
P07196
KDa
68
Vial with antibody
in solution
NCBI GENE nr
4747
GENE symbol
NEFL
Antigene name
neurofilament, light polypeptide
Source
Homo sapiens
Protein nr
P07196
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps