Gene info
Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.
Gene names
NFH, KIAA0845, NFH, 200 kDa neurofilament protein, NF-H
Antibodie's label
unlabelled serum
Purity
Total IgY fraction
Ab raised in
Chicken
Type
Polyclonal
Spicific to
Specific for the ~200k Neurofilament H protein.
Antigen
Purified bovine NF-H.
Immuno application
Western Blot, immuno-histo-chemistry
Keep at
Neurofilament NF-H antibody can be stored at -20 grades C and is stable at -20 grades C for at least 1 year.
Works with
Human, Mouse, Rat, Chicken
Omim nr
226726294
Ncbi nr
P12036
KDa
200
Vial with antibody
in solution
NCBI GENE nr
4744
GENE symbol
NEFH
Antigene name
neurofilament, heavy polypeptide
Source
Homo sapiens
Protein nr
P12036
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps