anti-ERBB2 Antibody

Gene info

A tyrosine kinase receptor in the EGF-receptor family. ErbB2 does not bind ligand on its own, but acts as an amplifier in heterodimers with ErbB1, (EGFR), ErbB3, or ErbB4. Amplification of the ErbB2 gene and overexpression of ErbB2 protein is associated with breast cancer (~25% of cases), and anti-ErbB2 therapeutics (e.g. Herceptin, an anti-ErbB2 monoclonal antibody) are sometimes effective in treating these cases. Overexpression of ErbB2 has also been indicated as a factor in prostate cancer.

Gene names

ERBB2, C-erb B2/neu protein, CD340, HER2, Herstatin, MLN 19, HER-2, Neu, NGL, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, CD340 antigen, MLN19, p185erbB2, TKR1

Antibodie's label

unlabelled serum

Purity

Immunoaffinity Chromatography

Ab raised in

Chicken

Type

Polyclonal

Immunoglobulin

IgY

Antigen

ERBB2 antibody was made against amino acids 153 to 433 of ERBB2 (Human).

Immuno application

Western Blot, immuno-histo-chemistry, immuno-cyto-chemistry

Antibody advice

ERBB2 antibody can be used in immunohistochemistry starting at 10 ug/mL.

Suspention, pH, azide

PBS. No preservative added.

Keep at

ERBB2 antibody should be stored at -20 grades C. As with all antibodies avoid freeze/thaw cycles.

Works with

Human, Mouse, Rat

Omim nr

119533

Ncbi nr

P04626

Vial with antibody

in solution

NCBI GENE nr

2064

GENE symbol

ERBB2

Antigene name

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2

Source

Homo sapiens

Protein nr

P04626

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Properties

If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

French translation

anticorps