This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. SMNDC1 is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
Gene names
SMNDC1, SMNR, SPF30, TDRD16C
Antibodie's label
unlabelled serum
Purity
Antibody is purified by peptide affinity chromatography method.
Ab raised in
Rabbit
Type
Polyclonal
Antigen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMNDC1.
Immuno application
ELISA, Western Blot
Antibody advice
SMNDC1 antibody can be used for detection of SMNDC1 by ELISA at 1:1562500. SMNDC1 antibody can be used for detection of SMNDC1 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Suspention, pH, azide
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Keep at
For short periods of storage (days) store at 4 grades C. For longer periods of storage, store SMNDC1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
Works with
Human, Mouse, Rat
Omim nr
5032113
Ncbi nr
NP_005862
KDa
27 kDa
Vial with antibody
Lyophilized
Quantity per ml
1 mg/ml
NCBI GENE nr
10285
GENE symbol
SMNDC1
Antigene name
survival motor neuron domain containing 1
Source
Homo sapiens
Protein nr
O75940
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
