Gene info
Neurotrypsin Antibody: Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.
Gene names
Neurotrypsin Antibody: MRT1, BSSP3, BSSP-3, Neurotrypsin, Leydin
Antibodie's label
unlabelled serum
Purity
Neurotrypsin Antibody is affinity chromatography purified via peptide column.
Ab raised in
Rabbit
Type
Polyclonal
Immunoglobulin
IgG
Antigen
Neurotrypsin antibody was made against a 23 amino acid synthetic peptide from near the amino terminus of human neurotrypsin.
Immuno application
ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
Antibody advice
Neurotrypsin antibody can be used for detection of neurotrypsin by Western blot at 0.5 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
Suspention, pH, azide
Neurotrypsin Antibody is supplied in PBS containing 0.02% sodium azide.
Keep at
Neurotrypsin antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Works with
Human, Mouse, Rat
Omim nr
2661424
Ncbi nr
CAA04816
Vial with antibody
in solution
Quantity per ml
1 mg/mL
NCBI GENE nr
8492
GENE symbol
PRSS12
Antigene name
protease, serine, 12 (neurotrypsin, motopsin)
Source
Homo sapiens
Protein nr
P56730
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation
anticorps