Long name
Neurokinin 1 Receptor Antibody
Also known as
Neurokinin 1 Receptor Antibody
Category
Primary Antibodies
Conjugation
Unconjugated
Target Antigen
Neurokinin 1 Receptor
Specificity
This is a highly specific antibody against Neurokinin 1 Receptor.
Modification(s)
None
Modification site(s)
Unmodified antibody
Clonality
Polyclonal antibody
Clone number
Polyclonal antibody
Concentration
1ug per 1ul
Immunogen range
2-50/407
Subcellular location
Extracellular
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Neurokinin 1 Receptor
Gene ID number
6869
Swiss Prot
P25103
Tested Applications
WB, IHC-P, IF(IHC-P)
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Cross reactivity
Human, Mouse, Rat
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigen
This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Purification method
This antibody was purified via Protein A.
Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym names
SPR; NK1R; NKIR; TAC1R; Substance-P receptor; NK-1 receptor; NK-1R; Tachykinin receptor 1; TACR1
Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
French translation
anticorps