c-erbB2 (Herstatin, V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) CD340, C-erbB-2, HER2, HER-2, HER-2/neu, MLN 19, NEU proto-oncogene, NGL, p185erbB2, Receptor tyrosine-protein kinase erbB-2[c-erbB2]

Products_type

Antibody

Reactivity

Human

Virus

leukemia

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.