Source
Prokaryotic expression
Predicted Molecular Mass(KD)
26.5kDa
Accurate Molecular Mass(KD)
25kDa
Organism species
Homo sapiens (Human)
Item Name
Cholinergic Receptor, Nicotinic, Alpha 4
Alternative Names
CHR-NA4; CHRN-A4; BFNC; EBN; EBN1; NACRA4; N-AChRA4; NAChRA4; N-AChR-A4; Neuronal Acetylcholine Receptor Alpha 4
Research Area
Signal transduction;Neuro science;
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Isoelectric Point
5.3
Purity
> 95%
Protein length
Asn49~Leu242
Tag
two N-terminal Tags, His-tag and T7-tag
Expression System
Prokaryotic expression
Application
Positive Control; Immunogen; SDS-PAGE; WB.
Description
The Recombinant Cholinergic Receptor, Nicotinic, Alpha 4 (CHRNa4) is a α- or alpha protein sometimes glycoprotein present in blood.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Additional source
Recombinants or rec. proteins
Group
recombinants