Description
Recombinant Human Cholinergic Receptor, Nicotinic, Alpha 4 expressed in: E.coli
Specifications
Host species: Homo sapiens (Human); Expression system: E.coli; Expression region: Asn49~Leu242; Purity: > 95%; Endotoxin level:
Additional_information
Uniprot ID: P43681; Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.; Form: Freeze-dried powder; Predicted Molecular Mass (KD): 26.5kDa; Isoelectric Point: 5.3
Storage_and_shipping
Shipped on ice packs. Upon receipt keep at 2-8 °C for up to 1 month. For long term storage prepare working aliquots and keep frozen at -20 or -80 °C. Avoid repeated freezing and thawing.
Notes
Research Use Only.
Additional description
The Recombinant Cholinergic Receptor, Nicotinic, Alpha 4 (CHRNa4) is a α- or alpha protein sometimes glycoprotein present in blood.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Source
Recombinants or rec. proteins
Group
recombinants