NPS/Neuropeptide S Antibody, Biotin Conjugated

Basic informations

  • Size: 0.1ml
  • Catalog number: bs-11428R-Biotin
  • Price: 333.00EUR
NPS/Neuropeptide S Antibody, Biotin Conjugated

Long name

NPS/Neuropeptide S Polyclonal Antibody, Biotin Conjugated

Category

Conjugated Primary Antibodies

Conjugation

Biotin

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

NPS/Neuropeptide S

Specificity

This is a highly specific antibody against NPS/Neuropeptide S.

Modification

Unmodified

Modification site

None

Clonality

Polyclonal

Clone

Polyclonal antibody

Concentration

1ug per 1ul

Source

KLH conjugated synthetic peptide derived from mouse Neuropeptide S

Gene ID number

100043254

Tested applications

IHC-P

Recommended dilutions

IHC-P(1:100-500)

Crossreactivity

Mouse

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Antigen background

Neuropeptides are regulators of synaptic transmission and their effects are mediated by G-protein coupled receptors. NPS (Neuropeptide S) is a 20 amino acid peptide cleaved from a larger precursor that contains a hydrophobic signal peptide and proteolytic cleavage processing sites. The N-terminal residue of NPS is always a serine regardless of the species. NPS is predominantly found in the central nervous system and plays an important role regulating sleep/wake functions, locomotion, arousal/anxiety responses and food intake. NPS functions by binding and activating its receptor, NPSR, and increasing intracellular calcium levels thereby acting as an excitatory transmitter. In addition, NPS stimulates the hypothalamo-pituitary adrenal (HPA) axis via the release of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP). NPS and its receptor NPSR may also play a role in asthma pathogenesis.

Purification method

This antibody was purified via Protein A.

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

Excitation Emission

N/A

Synonyms

NeuropeptideS; Neuropeptide-S; NPS; NPS_MOUSE.

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.

Additional conjugation

Biotinylated

French translation

anticorps