Long name
Neurokinin B receptor Antibody, HRP Conjugated
Category
Conjugated Primary Antibodies
Conjugation
HRP
Host Organism
Rabbit (Oryctolagus cuniculus)
Target Antigen
Neurokinin B receptor
Specificity
This is a highly specific antibody against Neurokinin B receptor.
Modification
Unmodified
Modification site
None
Clonality
Polyclonal
Clone
Polyclonal antibody
Concentration
1ug per 1ul
Immunogen_range
220-245/465
Subcellular location
Extracellular
Source
KLH conjugated synthetic peptide derived from human NKR
Gene ID number
6870
Swiss Prot
P29371
Tested applications
WB, IHC-P
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500)
Crossreactivity
Human, Mouse, Rat
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Antigen background
This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.
Purification method
This antibody was purified via Protein A.
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Excitation Emission
N/A
Synonyms
NKR; HH11; NK3R; NK-3R; TAC3RL; Neuromedin-K receptor; NK-3 receptor; Neurokinin B receptor; Tachykinin receptor 3; TACR3; TAC3R
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
Additional conjugation
HRP Conjugated
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
French translation
anticorps