Neuropilin-1 Antibody, Cy5.5 Conjugated

Basic informations

  • Size: 0.1ml
  • Catalog number: bs-0693R-Cy5.5
  • Price: 350.00EUR
Neuropilin-1 Antibody, Cy5.5 Conjugated

Long name

Neuropilin-1 Polyclonal Antibody, Cy5.5 Conjugated

Category

Conjugated Primary Antibodies

Conjugation

Cy5.5

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

Neuropilin 1

Specificity

This is a highly specific antibody against Neuropilin 1.

Modification

Unmodified

Modification site

None

Clonality

Polyclonal

Clone

Polyclonal antibody

Concentration

1ug per 1ul

Immunogen_range

880-923/923

Subcellular location

Cytoplasm

Source

KLH conjugated synthetic peptide derived from human neuropilin-1

Gene ID number

8829

Swiss Prot

O14786

Tested applications

IF(IHC-P)

Recommended dilutions

IF(IHC-P)(1:50-200)

Crossreactivity

Human, Mouse, Rat

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Antigen background

The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.

Purification method

This antibody was purified via Protein A.

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

Excitation Emission

675nm/694nm

Synonyms

NP1; NRP; BDCA4; CD304; VEGF165R; Neuropilin-1; Vascular endothelial cell growth factor 165 receptor; NRP1

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.

Additional conjugation

Cy5.5,Cy5.5

Conjugated

These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.

French translation

anticorps