Also known as
NEUROFILAMENT L
Other names
Neurofilament light polypeptide; Neurofilament light polypeptide; N/A; N/A; 68 kDa neurofilament protein; Neurofilament triplet L protein
Category
Antibodies
Subcategory
Mnoclonal antibodies
Gene name
N/A; NEFL; N/A; NF-L
Gene name synonims
N/A; NEFL; N/A; NF-L
Other gene names
N/A; NEFL; N/A; NF-L
Clonality
Monoclonal
Immunoglobulin isotype
IgG1
Clone
DA2
Host organism
Mouse (Mus musculus)
Species reactivity
Pig; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
NEUROFILAMENT L This item recognises neurofilament L (NF-L), the most abundant of the three nurofilament proteins (NF-H, NF-M and NF-L). Neurofilaments are 10nm or intermediate filaments found specifically in neurons, with especially high concentrations along the axons, where they appear to control axonal diameter. Defects in NF-L are the cause of Charcot-Marie-Tooth disease types 1F and 2E, characterised by loss of muscle tissue and touch sensation.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Purification method
N/A
Form/Appearance
S/N (Tissue Culture Supernatant - liquid)
Concentration
N/A
Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
Tested applications:
Western Blot (WB), Immunofluorescence (IF)
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name
Mus musculus
About
Pigs and the smaller guinea pigs are frequent used as models for humans.
French translation
anticorps