Also known as
TrkB
Other names
trkB; BDNF/NT-3 growth factors receptor; BDNF/NT-3 growth factors receptor; trk-B; OTTHUMP00000021573; OTTHUMP00000021574; OTTHUMP00000021575; OTTHUMP00000021576; OTTHUMP00000021577; trkB tyrosine kinase; tyrosine kinase receptor B; BDNF-tropomyosine receptor kinase B; neurotrophic tyrosine kinase, receptor, type 2; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase
Category
Antibodies
Subcategory
Mnoclonal antibodies
Gene name
NTRK2; NTRK2; TRKB; GP145-TrkB; TRKB
Gene name synonims
NTRK2; NTRK2; TRKB; GP145-TrkB; TRKB
Other gene names
NTRK2; NTRK2; TRKB; GP145-TrkB; TRKB
Clonality
Monoclonal
Immunoglobulin isotype
IgG2
Clone
9F396
Host organism
Rat (Rattus norvegicus)
Source organism
Mouse (Mus musculus)
Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes mouse TrkB. Does not react with mouse TrkC.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Purification method
Purified
Form/Appearance
Supplied as a lyophilized powder in PBS. Reconstitute in 500ul 40-50% glycerol, PBS.
Concentration
N/A
Storage and shipping
Lyophilized powder Store the antibody at +4 degrees Celsius for short term storage.. Reconstitute to nominal volume by adding sterile 40-50% glycerol and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 3 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested applications:
Western Blot (WB), Immunohistochemistry (IHC)
Tissue
brain
Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.