Also known as
FRS2
Other names
fibroblast growth factor receptor substrate 2; Fibroblast growth factor receptor substrate 2; fibroblast growth factor receptor substrate 2; FGFR substrate 2; FGFR signalling adaptor; FGFR-signaling adaptor SNT; suc1-associated neurotrophic factor target 1; fibroblast growth factor receptor substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1
Category
Antibodies
Subcategory
Mnoclonal antibodies
Gene name
FRS2; FRS2; SNT; SNT1; FRS2A; SNT-1; FRS2alpha; FGFR substrate 2; SNT-1
Gene name synonims
FRS2; FRS2; SNT; SNT1; FRS2A; SNT-1; FRS2alpha; FGFR substrate 2; SNT-1
Other gene names
FRS2; FRS2; SNT; SNT1; FRS2A; SNT-1; FRS2alpha; FGFR substrate 2; SNT-1
Clonality
Monoclonal
Immunoglobulin isotype
IgG2b
Clone
8B20
Host organism
Mouse (Mus musculus)
Source organism
Human (Homo sapiens)
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes human FRS2.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Purification method
Affinity Purified by Protein G affinity chromatography.
Form/Appearance
Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
Concentration
N/A
Storage and shipping
Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested applications:
ELISA (EL/EIA), Flow Cytometry (FC/FACS)
Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.Induced protein genes, factors or kinases, increase the production of (an enzyme or other protein) at the level of genetic transcription.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.