Alternative name1
Anti-TrkA, phosphorylated (Tyr490) (Tyrosine Kinase Receptor A, Nerve Growth Factor Receptor, NGFR, Neurotrophin Receptor, NTR)
Alternative name2
TrkA, phosphorylated (Tyr490) (Tyrosine Kinase Receptor A, Nerve Growth Factor Receptor, NGFR, Neurotrophin Receptor, NTR)
Alternative name3
TrkA, phosphorylated (Tyr490) (Tyrosine Kinase Receptor A, Nerve Growth Factor Receptor, NGFR, Neurotrophin Receptor, NTR)
Alternative name4
TrkA
Alternative name5
Anti -TrkA, phosphorylated (Tyr490) (Tyrosine Kinase Receptor A, Nerve Growth Factor Receptor, NGFR, Neurotrophin Receptor, NTR)
Other names
TRKA; High affinity nerve growth factor receptor; high affinity nerve growth factor receptor; Oncogene TRK; OTTHUMP00000038736; OTTHUMP00000234666; OTTHUMP00000234667; OTTHUMP00000234668; OTTHUMP00000234669; tyrosine kinase receptor A; TRK1-transforming tyrosine kinase protein; neurotrophic tyrosine kinase, receptor, type 1; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; p140-TrkA
Gene name
N/A
Gene name synonims
N/A
Other gene names
NTRK1; NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; DKFZp781I14186; TRK
Category
Antibodies
Clonality
Polyclonal
Immunoglobulin isotype
IgG
Clone
Polyclonal antibody
Host organism
Host: Rabbit; Source: Human
Species reactivity
Human, Mouse, Rat
Specificity and cross-reactivity
Recognizes endogenous levels of rat Trk only when phosphorylated at Tyr490. Can also detect the corresponding residues of phosphorylated TrkB and TrkC. Species sequence homology: human, mouse.
Purification method
Affinity Purified by Protein A affinity chromatography.
Form/Appearance
Supplied as liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. No preservative added.
Concentration
N/A
Storage and shipping
Store at 4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested for:
ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Tissue
nerve
Additional description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.