Neuropilin-1 Antibody, ALEXA FLUOR 350

Basic informations

  • Size: 100ul
  • Catalog number: bs-0693R-A350
  • Price: 380.00EUR
Neuropilin-1 Antibody, ALEXA FLUOR 350

Long name

Neuropilin-1 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated

Also known as

Anti-Neuropilin 1 PAb ALEXA FLUOR 350

Category

Conjugated Primary Antibodies

Conjugated with

ALEXA FLUOR® 350

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

Neuropilin 1

Specificity

This is a highly specific antibody against Neuropilin 1.

Modification

Unmodified

Modification Site

None

Clonality

Polyclonal

Clone

Polyclonal antibody

Concentration

1ug per 1ul

Immunogen range

880-923/923

Subcellular location

Cytoplasm

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human neuropilin-1

Gene ID Number

8829

Swiss Prot

O14786

Tested applications

IF(IHC-P)

Recommended dilutions

IF(IHC-P)(1:50-200)

Crossreactivity

Human, Mouse, Rat

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Background of the antigen

The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.

Purification

Purified by Protein A.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Excitation emission

343nm/442nm

Synonyms

NP1; NRP; BDCA4; CD304; VEGF165R; Neuropilin-1; Vascular endothelial cell growth factor 165 receptor; NRP1

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Conjugation

Alexa Fluor,ALEXA FLUOR 350

French translation

anticorps