Long name
NPS/Neuropeptide S Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
Also known as
Anti-NPS/Neuropeptide S PAb ALEXA FLUOR 350
Category
Conjugated Primary Antibodies
Conjugated with
ALEXA FLUOR® 350
Host Organism
Rabbit (Oryctolagus cuniculus)
Target Antigen
NPS/Neuropeptide S
Specificity
This is a highly specific antibody against NPS/Neuropeptide S.
Modification
Unmodified
Modification Site
None
Clonality
Polyclonal
Clone
Polyclonal antibody
Concentration
1ug per 1ul
Source
KLH conjugated synthetic peptide derived from mouse Neuropeptide S
Gene ID Number
100043254
Tested applications
IF(IHC-P)
Recommended dilutions
IF(IHC-P)(1:50-200)
Crossreactivity
Mouse
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen
Neuropeptides are regulators of synaptic transmission and their effects are mediated by G-protein coupled receptors. NPS (Neuropeptide S) is a 20 amino acid peptide cleaved from a larger precursor that contains a hydrophobic signal peptide and proteolytic cleavage processing sites. The N-terminal residue of NPS is always a serine regardless of the species. NPS is predominantly found in the central nervous system and plays an important role regulating sleep/wake functions, locomotion, arousal/anxiety responses and food intake. NPS functions by binding and activating its receptor, NPSR, and increasing intracellular calcium levels thereby acting as an excitatory transmitter. In addition, NPS stimulates the hypothalamo-pituitary adrenal (HPA) axis via the release of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP). NPS and its receptor NPSR may also play a role in asthma pathogenesis.
Purification
Purified by Protein A.
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission
343nm/442nm
Synonyms
NeuropeptideS; Neuropeptide-S; NPS; NPS_MOUSE.
Properties
For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation
Alexa Fluor,ALEXA FLUOR 350
French translation
anticorps