NF2/Neurofibromin 2 Antibody, ALEXA FLUOR 594

Basic informations

  • Size: 100ul
  • Catalog number: bs-1366R-A594
  • Price: 380.00EUR
NF2/Neurofibromin 2 Antibody, ALEXA FLUOR 594

Long name

NF2/Neurofibromin 2 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated

Also known as

Anti-NF2/Neurofibromin 2 PAb ALEXA FLUOR 594

Category

Conjugated Primary Antibodies

Conjugated with

ALEXA FLUOR® 594

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

NF2/Neurofibromin 2

Specificity

This is a highly specific antibody against NF2/Neurofibromin 2.

Modification

Unmodified

Modification Site

None

Clonality

Polyclonal

Clone

Polyclonal antibody

Concentration

1ug per 1ul

Immunogen range

430-480/590

Subcellular location

Intracellular

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NF2

Gene ID Number

4771

Swiss Prot

P35240

Tested applications

IF(IHC-P)

Recommended dilutions

IF(IHC-P)(1:50-200)

Crossreactivity

Human, Mouse, Rat

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Background of the antigen

Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.

Purification

Purified by Protein A.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Excitation emission

590nm/617nm

Synonyms

ACN; SCH; BANF; Merlin; Moesin-ezrin-radixin-like protein; Neurofibromin-2; Schwannomerlin; Schwannomin; NF2

Properties

For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Conjugated

Alexa conjugate 1

French translation

anticorps