NPS/Neuropeptide S Antibody, ALEXA FLUOR 647

Basic informations

  • Size: 100ul
  • Catalog number: bs-11422R-A647
  • Price: 380.00EUR
NPS/Neuropeptide S Antibody, ALEXA FLUOR 647

Long name

NPS/Neuropeptide S Polyclonal Antibody, ALEXA FLUOR 647 Conjugated

Also known as

Anti-NPS/Neuropeptide S PAb ALEXA FLUOR 647

Category

Conjugated Primary Antibodies

Conjugated with

ALEXA FLUOR® 647

Host Organism

Rabbit (Oryctolagus cuniculus)

Target Antigen

NPS/Neuropeptide S

Specificity

This is a highly specific antibody against NPS/Neuropeptide S.

Modification

Unmodified

Modification Site

None

Clonality

Polyclonal

Clone

Polyclonal antibody

Concentration

1ug per 1ul

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Neuropeptide S

Gene ID Number

594857

Tested applications

IF(IHC-P)

Recommended dilutions

IF(IHC-P)(1:50-200)

Crossreactivity

Human

Cross-reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Background of the antigen

Neuropeptides are regulators of synaptic transmission and their effects are mediated by G-protein coupled receptors. NPS (Neuropeptide S) is a 20 amino acid peptide cleaved from a larger precursor that contains a hydrophobic signal peptide and proteolytic cleavage processing sites. The N-terminal residue of NPS is always a serine regardless of the species. NPS is predominantly found in the central nervous system and plays an important role regulating sleep/wake functions, locomotion, arousal/anxiety responses and food intake. NPS functions by binding and activating its receptor, NPSR, and increasing intracellular calcium levels thereby acting as an excitatory transmitter. In addition, NPS stimulates the hypothalamo-pituitary adrenal (HPA) axis via the release of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP). NPS and its receptor NPSR may also play a role in asthma pathogenesis.

Purification

Purified by Protein A.

Storage conditions

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.

Excitation emission

650nm/665nm

Synonyms

NeuropeptideS; Neuropeptide-S; NPS; NPS_HUMAN.

Properties

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-NPS/Neuropeptide S exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Conjugation

Alexa Fluor,ALEXA FLUOR 647

French translation

anticorps