Leucine-Rich Repeat Transmembrane Neuronal Protein 2; Leucine-Rich Repeat Neuronal 2 Protein; LRRTM2; KIAA0416; LRRN2
NA
Cys34-Arg422
C-6His
O43300
Human cells
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
>95% as determined by reducing SDS-PAGE.
<1.0 EU per µg as determined by LAL test.
Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
45.6 kDa
74 kDa
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Leucine-Rich Repeat Transmembrane Neuronal Protein 2 (LRRTM2) is a single-pass type I membrane protein that belongs to the LRRTM family. It contains ten LRR (leucine-rich) repeats, one LRRCT domain, and one LRRNT domain. LRRTM2 is expressed in neuronal tissues, and it interacts with DLG4 and NRXN1. LRRTM2 has been suggested to be involved in the development and maintenance of excitatory synapses in the vertebrate nervous system. LRRTM2 also regulates the surface expression of AMPA receptors. LRRTM2 acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Recombinants or rec. proteins
recombinants